The HLA-G 14-bp polymorphism and recurrent implantation failure: a meta-analysis
نویسندگان
چکیده
منابع مشابه
Association between HLA-G 14-bp insertion/deletion polymorphism and cancer risk: a meta-analysis.
PURPOSE A number of studies have investigated the association between human leukocyte antigen-G (HLA-G) 14-bp insertion/deletion polymorphism and cancer risk, but the results remain controversial. In this study we aimed to clarify whether this association really exists. METHODS We carried out a meta-analysis of 8 studies including 1179 cases and 2795 controls from PubMed and Chinese language ...
متن کاملthe hla-g 14-bp insertion/ deletion polymorphism in recurrent spontaneous abortion among iranian women
hla-g is a non-classical hla class ib molecule with limited protein variability generated by alternative splicing. hla-g displays immunotolerant properties and hence plays important roles in the maintenance of a successful pregnancy and maternal tolerance of the semiallogenic fetus. polymorphism of the hla-g gene may potentially affect the biological properties of the protein, and a ...
متن کاملassociation of the maternal 14-bp insertion/deletion polymorphism in the histocompatibility leukocyte antigen g gene with recurrent implantation failure
background: implantation failure of blastocyst is one of the main reasons of failure to become pregnancy following use of assisted reproductive techniques. hla-g, one of the non-classic hla subtypes, seems to have a vital role in neutralizing of mother immune system. according to importance of ins/del polymorphism of hla-g in regulation of hla-g expression, it seems that this polymorphism has a...
متن کاملThe HLA-G 14-bp Insertion/ Deletion Polymorphism in Recurrent Spontaneous Abortion among Iranian Women
HLA-G is a non-classical HLA class Ib molecule with limited protein variability generated by alternative splicing. HLA-G displays immunotolerant properties and hence plays important roles in the maintenance of a successful pregnancy and maternal tolerance of the semiallogenic fetus. Polymorphism of the HLA-G gene may potentially affect the biological properties of the protein, and a 14-bp inser...
متن کاملAssociation of the maternal 14-bp insertion/deletion polymorphism in the histocompatibility leukocyte antigen G gene with recurrent implantation failure
BACKGROUND Implantation failure of blastocyst is one of the main reasons of failure to become pregnancy following use of Assisted Reproductive Techniques. HLA-G, one of the non-classic HLA subtypes, seems to have a vital role in neutralizing of mother immune system. According to importance of ins/del polymorphism of HLA-G in regulation of HLA-G expression, it seems that this polymorphism has an...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2017
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-017-0994-3